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SPECTRUMClinical Research Labs

Current Biospecimen Needs

These Are Our Current Needs

Spectrum Clinical Research Labs is seeking qualified collection sites, physician networks, hospitals, biobanks, and biospecimen partners who can fulfill active research collection requests.

Client Confidentiality

Spectrum Clinical Research Labs protects the identity and proprietary information of its clients. Active needs are presented without client names, project identifiers, budgets, or other confidential commercial information. Additional project details are shared only with qualified partners as appropriate and subject to applicable confidentiality requirements.

17active needs
8research categories

Partial availability and prospective collection capacity are welcome where applicable.

Updated October 29, 2026 · availability and specifications confirmed per project

Current sourcing requests

Hematology / Oncology

4 needs

Matched untreated DLBCL sets

Sourcing / availability pending confirmation
Indication / population
Untreated diffuse large B-cell lymphoma; no subtype, stage, or demographic restrictions.
Specimen
Residual diagnostic lymph-node tissue and matched pretreatment blood from the same donor. FFPE: 12 × 10 µm sections, target ≥10% tumor. Whole blood: 30 mL, yielding buffy coat ≥0.5 mL and EDTA plasma ≥8 mL. PBMC not required.
Quantity / volume
Up to 50 matched sets; partial quantities welcome.
Processing / shipping
Collect blood in K2EDTA. Process plasma within 4 hours; freeze at −80 °C and ship on dry ice.
Documentation / data
Confirm pretreatment status, same-donor matching, tissue tumor content, and available collection documentation.
What to send us
Available matched sets or prospective capacity, tissue/blood handling details, and estimated accrual.
Can you fulfill this need? Request collection quote

Fresh leukemia & myeloid specimens

Sourcing / availability pending confirmation
Indication / population
AML, ALL (B-ALL/T-ALL), APL, MPAL, MDS, MPN, CML, CLL, hairy cell leukemia (HCL), and chronic myelomonocytic leukemia (CMML). Other leukemia/myeloid indications may be reviewed by inquiry. Active or symptomatic disease only; pretreatment or on-treatment accepted, no remission. Relapsed/refractory before next treatment preferred.
Specimen
Fresh peripheral blood (~10.5–17.5 mL) in K2EDTA (BD 367863) or PAXgene Blood RNA (BD 762165). Priority marrow: ≥2.5 mL K2EDTA, then ≥1 mL PAXgene Bone Marrow RNA (BD 764114), leaving ≥1.2 mL EDTA.
Quantity / volume
Share expected accrual by indication and specimen type.
Processing / shipping
Fresh only, within the U.S.; ship day of draw and arrive within 3 days. Chill at 2–8 °C with temperature logger/Nanocool; weekday delivery only.
Documentation / data
Ethics/IRB documentation and consent form required.
What to send us
Indications available, accrual rate, specimen formats, shipping capability, ethics/IRB documentation, and consent form availability.
Can you fulfill this need? Request collection quote

CLL K2EDTA whole blood

Sourcing / availability pending confirmation
Indication / population
Donors with confirmed chronic lymphocytic leukemia (CLL). Treatment-naive donors preferred, not mandatory.
Specimen
K2EDTA whole blood, 8 mL per donor.
Quantity / volume
Donor quantity and feasibility not yet confirmed; availability subject to confirmation.
Processing / shipping
Processing and shipping details to confirm per project.
Documentation / data
De-identified donor demographics, treatment history, and CBC results requested.
What to send us
What could be provided by November 30, 2026, plus donor quantity, treatment status mix, availability of demographics, treatment history and CBC data, processing, and shipping capability.
Can you fulfill this need? Request collection quote

AML with UBTF tandem duplication

Sourcing / availability pending confirmation
Indication / population
UBTF tandem duplication (UBTF-TD) positive; AML preferred, other indications considered.
Specimen
Genomic DNA extracted from BMMC or PBMC preferred; cell pellets acceptable.
Quantity / volume
Approximately 25 retrospective specimens.
Processing / shipping
Describe extraction method, storage, and shipping conditions.
Documentation / data
Molecular confirmation of UBTF-TD by NGS, WGS, PCR, or comparable method.
What to send us
Number of confirmed specimens, indication, material type (gDNA or cell pellet), confirmation method and lead time.
Can you fulfill this need? Request collection quote

Current sourcing requests

Autoimmune

4 needs

Longitudinal autoimmune collections

Sourcing / availability pending confirmation
Indication / population
SLE, Sjögren’s, IgA nephropathy, myasthenia gravis, rheumatoid arthritis, multiple sclerosis, and healthy donors.
Specimen
Viable frozen PBMC from approximately 20 mL whole blood per time point, with matched plasma and serum.
Quantity / volume
Paired time points before/after treatment and flare/recovery, tracked separately.
Processing / shipping
Document viability, cryopreservation, and matched-sample handling for each time point.
Documentation / data
Treatment annotation and available clinical measurements linked to each de-identified time point.
What to send us
Indication-specific recruitment capacity, longitudinal follow-up capability, PBMC processing workflow, and available annotations.
Can you fulfill this need? Request collection quote

Fresh autoimmune whole blood

Sourcing / availability pending confirmation
Indication / population
Sjögren’s, systemic sclerosis, and lupus nephritis.
Specimen
K2EDTA whole blood, 30–50 mL per donor.
Quantity / volume
Up to 20 donors per indication.
Processing / shipping
Fresh overnight shipment at 2–8 °C.
Documentation / data
Full informed consent; de-identified demographics, collection date, and clinical disease activity score when available.
What to send us
Donor access by indication, expected accrual, consent and clinical-data availability, and chilled overnight shipping capability.
Can you fulfill this need? Request collection quote

Rheumatoid arthritis fresh blood collection

Sourcing / availability pending confirmation
Indication / population
Rheumatoid arthritis; eligibility criteria to confirm per project.
Specimen
Fresh blood; collection tube and volume to confirm per project.
Quantity / volume
Volume and quantity per project.
Processing / shipping
Processing and shipping requirements to confirm per project.
Documentation / data
Consent/ethics requirements and available de-identified clinical data to confirm per project.
What to send us
Indication, specimen type, estimated quantity, geography, processing, shipping capability, and lead time.
Can you fulfill this need? Request collection quote

Rheumatoid arthritis synovial tissue — anti-TNF response cohorts

Sourcing / availability pending confirmation
Indication / population
RA donors with documented anti-TNF response status, including responders and non-responders, with pre-treatment and post-treatment time points; osteoarthritis controls.
Specimen
Synovial tissue; exact preservation/format and RNA suitability must be confirmed by supplier response before fulfillment.
Quantity / volume
3 RA responders and 3 RA non-responders, with pre/post anti-TNF tissue requested for each cohort, plus 2 OA controls. Partial or unmatched control-only material does not fulfill the request; partial quantities can be submitted for review only.
Processing / shipping
Please state format (FFPE, frozen, or fresh), section/block dimensions or tissue mass, fixation/freezing method, storage, and shipping.
Documentation / data
De-identified diagnosis, anti-TNF agent, responder/non-responder classification, pre/post time point, pairing status, pathology, available RNA quality/suitability, and consent/IRB or waiver.
What to send us
Qualifying donor counts by cohort and time point, pairing, format, RNA suitability, documentation, availability, and lead time.
Can you fulfill this need? Request collection quote

Current sourcing requests

Renal / Tissue

1 need

IgA nephropathy FFPE tissue

Sourcing / availability pending confirmation
Indication / population
Confirmed IgA nephropathy (IgAN). Retrospective cases.
Specimen
FFPE kidney biopsy tissue blocks; biopsy approximately 5 mm diameter if possible. Slides may be considered after specification review.
Quantity / volume
Up to 20 unique donors.
Processing / shipping
Retrospective FFPE blocks; describe storage and shipping conditions.
Documentation / data
Consent or IRB waiver. Required: de-identified demographics and confirmed diagnosis. Preferred when available: gd-IgA ELISA titers and proteinuria.
What to send us
Number of qualifying cases, block/biopsy dimensions, slide availability, available clinical data and lead time. Needed as soon as possible.
Can you fulfill this need? Request collection quote

Current sourcing requests

Infectious Disease

1 need

VZV-positive lesion swabs

Sourcing / availability pending confirmation
Indication / population
Varicella-zoster virus (VZV) positive, from shingles or chickenpox.
Specimen
Banked mucocutaneous lesion/skin swabs in universal transport medium (UTM).
Quantity / volume
20 banked positive swabs.
Processing / shipping
Describe storage temperature and shipping conditions.
Documentation / data
Confirmation of VZV-positive status and available de-identified data.
What to send us
Number of positive swabs available, confirmation method, storage conditions and lead time.
Can you fulfill this need? Request collection quote

Current sourcing requests

Biofluids

2 needs

Remnant CSF

Sourcing / availability pending confirmation
Indication / population
Remnant cerebrospinal fluid (CSF); exact population criteria to confirm per project. Related capability question: prospective synovial fluid collection is also of interest, separate from the immediate CSF requirement.
Specimen
Remnant cerebrospinal fluid (CSF); exact specimen criteria and aliquot volume to confirm per project.
Quantity / volume
Quantity and exact eligibility criteria to confirm per project. Please share estimated weekly capacity.
Processing / shipping
Describe sample handling, storage, and shipping conditions.
Documentation / data
Please describe any de-identified clinical or demographic information available with the samples.
What to send us
Weekly CSF capacity, whether samples are remnant/current inventory or prospective, handling/storage/shipping capability, available de-identified data and lead time, and whether prospective synovial fluid collection is available.
Can you fulfill this need? Request collection quote

Pediatric remnant coagulation specimens

Sourcing / availability pending confirmation
Indication / population
Pediatric residual/remnant diagnostic specimens for coagulation assays (examples: Anti-Xa, APTT-SS).
Specimen
Pediatric remnant diagnostic specimens suitable for coagulation assays; specimen types to be confirmed per project.
Quantity / volume
To be confirmed per project-specific requirements.
Processing / shipping
Processing, storage, and shipping requirements to be confirmed per project.
Documentation / data
Clinical data and consent or waiver requirements to be confirmed per project.
What to send us
Laboratory access, remnant specimen types available, assay coverage (e.g., Anti-Xa, APTT-SS), estimated capacity, and available documentation.
Can you fulfill this need? Request collection quote

Current sourcing requests

Lung / Tissue

2 needs

Lung cancer tissue

Sourcing / availability pending confirmation
Indication / population
Lung squamous cell carcinoma, lung adenocarcinoma, lung large cell carcinoma, and small cell lung carcinoma (SCLC).
Specimen
Frozen: squamous, adenocarcinoma, and SCLC. Fresh: large cell carcinoma. Target 0.2–1 g per donor for each type.
Quantity / volume
5–10 unique donors per histology.
Processing / shipping
For fresh large-cell carcinoma, provide collection-to-delivery time and preservation/transport medium. Describe frozen storage and shipping for other types.
Documentation / data
Histology confirmation and available de-identified donor/sample documentation.
What to send us
Available histologies, donor quantities, tissue weights, fresh transport timing/medium, and frozen shipping details.
Can you fulfill this need? Request collection quote

Fresh NSCLC tumor tissue

Sourcing / availability pending confirmation
Indication / population
Non-small cell lung cancer (NSCLC); primary or metastatic tumors accepted. Any treatment status and standard demographics accepted.
Specimen
Fresh NSCLC tumor resection tissue, minimum 250 mg per donor; intact or fragmented tissue accepted.
Quantity / volume
Target 25 unique donors. Prospective collection only; accrual and lead time are best efforts and not guaranteed.
Processing / shipping
Collect into DMEM with maximum ischemia time of 60 minutes. Ship cold on gel packs for Monday–Friday delivery.
Documentation / data
IRB approval and informed consent documentation; de-identified age, sex, race, primary diagnosis, comorbidities, and current medications.
What to send us
Prospective accrual capacity, collection geography, tumor-content assessment if available, transport timing, IRB/consent documentation, and best-estimate lead time.
Can you fulfill this need? Request collection quote

Current sourcing requests

Pathology / Tissue

2 needs

Pituitary Adenoma — Retrospective Tissue

Sourcing / availability pending confirmation
Indication / population
Pathology-confirmed pituitary adenoma, IHC positive for at least one of PRL, GH, TSH, FSH, or LH. Retrospective archived cases.
Specimen
One retrospective FFPE block per donor, fixed in 10% neutral buffered formalin, tissue area ≥4 mm². Digital H&E slide images must be available for QC review before final selection.
Quantity / volume
Up to 12 unique donors. Partial fulfillment accepted.
Processing / shipping
Digital H&E QC review precedes final block selection; not all reviewed blocks will be purchased. Ship at controlled room temperature with cold packs as agreed.
Documentation / data
Consent or IRB waiver; de-identified pathology, IHC results, and adenoma size data.
What to send us
Number of qualifying cases, available pathology/IHC/size data, estimated timeline and digital H&E availability.
Can you fulfill this need? Request collection quote

Other fresh tissue / tumor collections

Sourcing / availability pending confirmation
Indication / population
Other indications by inquiry; eligibility to confirm per project.
Specimen
Fresh tissue or tumor; specifications to confirm by inquiry.
Quantity / volume
Quantity and tissue weight to confirm per project.
Processing / shipping
Processing, preservation, shipping temperature, and delivery window to confirm per project.
Documentation / data
Consent/ethics requirements and available de-identified documentation to confirm per project.
What to send us
Indication, specimen type, estimated quantity, geography, processing, shipping capability, and lead time.
Can you fulfill this need? Request collection quote

Current sourcing requests

Healthy Controls

1 need

Healthy control frozen tissue

Sourcing / availability pending confirmation
Indication / population
Brain, liver, lung, heart, kidney, intestine, stomach, pancreas, spleen, colon, and muscle.
Specimen
Frozen healthy-control tissue, 0.2–1 g per donor.
Quantity / volume
5–10 unique donors per tissue type.
Processing / shipping
Provide storage and shipping conditions.
Documentation / data
Pathology/normal confirmation where applicable, donor clinical/demographic data, and consent/ethics documentation.
What to send us
Available tissue types, quantities per type, donor data, documentation, storage/shipping conditions and lead time.
Can you fulfill this need? Request collection quote

Work with Spectrum

Have a match or a related capability?

Specifications are subject to final project confirmation. Additional documentation may be requested before onboarding.

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